CORONAVIRUS INFO PROVIDED BY DR. JIM HARRIS –10/27/2021

A key F.D.A. advisory panel recommended the use of the Pfizer vaccine in 5- to 11-year-olds, who could start getting shots late next week.

Letter From Australia: A Never-Ending Pandemic?

(J. Harris: This is an excellent, readable, short letter regarding the Australian Covid experience.)

China locks down a northwestern city to subdue a small outbreak.

AND LASTLY:

GREETING S FROM THE FURHER BUNKER COMPLETE WITH GUARD DOG. We had a bit of wind this morning, but the bunker is warm and dry and the tornado went around us. 

MEANWHILE AT THE MOVIES:

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CORONAVIRUS INFO PROVIDED BY DR. JIM HARRIS –10/26/2021

WHEN WILL OUR NEXT LOCAL COVID SPIKE OCCUR? 

A. NEVER

B. WHEN THE WEATHER GETS COLD

C. IN ABOUT 6 MONTHS WITH A NEW VARIANT

ANSWER: ???  BUT SINCE WE ARE LARGELY UNVACCINATED LOCALLY,  IT WILL OCCUR AND IT WILL ALSO INVOLVE REPEAT INFECTIONS IN UNVACCINATED FOLKS. PRIOR DISEASE IS NOT PROTECTIVE. 

A Covid update (J. Harris: Excellent. Current.)

HOSPITAL DEPARTMENT CLOSURES (MOSTY OBSTETRICS)

(J. Harris: “Small town hospitals, not necessarily ‘Rural’ often are not busy enough to remain open.”

Long-term consequences of the misuse of ivermectin data

”…On March 31, 2021, WHO advised that ivermectin should only be used within clinical trials and not as part of routine clinical practice.4 This advice was followed by the manufacturer, Merck, that stated on Feb 4, 2021, that there is “no meaningful evidence for clinical activity or clinical efficacy in patients with COVID-19 disease”.5 Despite this, ivermectin is being routinely used in some Latin American settings amid recommendations from some governments and health professionals….Sustained misinformation can lead to diversion of limited health-care and government resources to addressing rumours rather than making genuine public heath progress. Proactive health promotion and education is needed right now to ensure that locally trusted actors and communicators (including, but not limited to, health-care workers) are aware of the uncertainty around the ivermectin evidence base for managing COVID-19, and that it remains a vital medicine for managing neglected tropical disease. Where advocacy emerged from official or high-level sources during the COVID-19 pandemic, we have concerns that the likelihood of mistrust within communities will increase. International and national global health policy stakeholders must be made aware that this mistrust could be an issue that needs addressing in both the short-term and medium-term future….”

If You’re Unvaccinated for Covid Can Your Doctor Refuse to Treat You?

LASTLY:

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CORONAVIRUS INFO PROVIDED BY DR. JIM HARRIS –10/25/2021

FROM BECKER CITATIONS:

1. What Amazon’s chief health officer says is the biggest workplace health challenge of the century

2. COVID-19 reinfection likely for unvaccinated, study suggests

”…”Reinfection can reasonably happen in three months or less… “Therefore, those who have been naturally infected should get vaccinated. Previous infection alone can offer very little long-term protection against subsequent infections…Researchers also predicted reinfection will become “increasingly common” as COVID-19 transitions into an endemic disease. 

FROM NEJM:

Uncomfortable Truths — What Covid-19 Has Revealed about Chronic-Disease Care in America

(J. Harris: A comprehensive review of the state of medical care in the US with suggestions for needed improvements. Readable.)

”…Covid-19 also made us walk backward and see the larger worldview, in the process revealing uncomfortable truths about the U.S. health care system — including our approach to managing chronic diseases…”

The Flawed Science of Antibody Testing for SARS-CoV-2 Immunity

(J. Harris: A very readable summary of Covid related antibodies and questions. I edited it a little. A few readers are interested in this area of study.)

”…“Individuals can have neutralizing antibodies and still get infected,…. “We know that higher antibody levels, specifically higher neutralizing antibody levels, are better. But we don’t know how high is high enough….So far, only one commercially available SARS-CoV-2 antibody test, from Ortho-Clinical Diagnostics, has been calibrated to the World Health Organization’s reference standard… the test sold through Epitome Risk Solutions’ subsidiary, FourthWall Testing, appeared to be an at-home version of the FDA-authorized GenScript cPass SARS-CoV-2 Neutralization Antibody Detection Kit, a surrogate assay that indirectly measures neutralizing antibodies. According to an FDA spokesperson, the cPass test does not have authorization for sample collection at home. And despite Epitome’s marketing hype, GenScript states that customers “should not interpret the results of this test as an indication or degree of immunity or protection from reinfection….[Actually],The immunological component that is associated with protection against severe disease is immunological memory B cells,.. “These cells aren’t making antibodies, but they remember that they have seen this SARS-CoV-2 spike protein before….circulating antibodies against the virus peak 2 or 3 months after natural infection or vaccination and then begin to decrease. But the immune system’s ability to mount a defense lasts longer. “Just because we’re seeing a decrease in antibody levels doesn’t necessarily mean that your immunity is gone,…We know from a lot of studies now that your memory T cells and memory B cells persist for at least 6 to 8 months and continue to evolve and mature, and none of that information is relayed by an antibody test….that reinfection with the virus activates memory B cells to differentiate into antibody-secreting cells. Because this process can take 3 to 5 days, it doesn’t stop SARS-CoV-2 infections from occurring, but it does help tamp down severe COVID-19. And that’s a success story….“The goal of the vaccine is to protect you against serious illness….Managing expectations for COVID-19 vaccines may be in order. “I think there was maybe an initial misunderstanding amongst the public that this would just halt all infections, and that’s just not the case,…     Ultimately…advice for avoiding a SARS-CoV-2 infection in the first place comes down to a now-familiar combination of measures: “getting vaccinated, frequently washing your hands, wearing a mask, and avoiding high congregate in-door settings, particularly in areas that have high case rates….”

AND LAST BUT NOT LEASED:

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How-can-dumb-get-any-dumber?

 Opinion: How-can-dumb-get-any-dumber?-when-it’s Texas-Rep.-Louie-Gohmert headline and story of the day

By George Smith  — October 23, 2021

“GOP congressman: Capitol riot defendants are being treated worse than ‘blood thirsty murderers’ at Guantanamo”

Story:

Speaking on the House floor this Friday, Texas GOP Rep. Louie Gohmert went to bat for defendants arrested and charged for participating in the riot at the U.S. Capitol on Jan. 6, saying that authorities are treating them worse than prisoners in the Guantanamo Bay Detention Camp in Cuba.

“The reports we’ve been getting indicate that the folks here that are being held in pre-trial confinement and are being punished, although that’s unconstitutional to punish somebody while they are waiting trial and have not been convicted, that they’re not treated nearly as well as bloodthirsty murderers that are being held in Guantanamo,” Gohmert said.

Gohmert went on to say that he’s visited Capitol riot defendants and that it’s “tragic that American citizens are being treated so much worse than individuals who want to destroy America.”

“Dumb” does not do justice to describing the act of mere “thinking” that describes this man’s lack f of moral perspective and mental acuity.

He is so dumb that Baylor should rescind his law degree. He is so dumb that anyone who voted for him  or will vote for him should not be allow to…fill in blank here.

His imbecilic remarks and actions  — from “anchor babies” to being promoted to “general” of “Trump’s Troops” to excusing the Jan. 6 insurrection, deaths of five people and his excusing actions of his supporters trying to bring down a mainstay of democracu as outlined in the Constitution — woukd be laughable if he were not an elected official.

His First District supporters cannot continue to believe this man is a patriot and expresses the views of East Texas. East Texans, by and large,  are hard working, Bible believers who know God in his wisdom and Jesus in his teachings would cast the likes of Louie the Lip into the fiery depths of hell rather than listen to the insane drivel flowing from his lie-laced tongue.

There is no love in Louie, no empathy (except for the lies necessary to hold onto power), no help for the poor and oppressed, you know … Jesus stuff!

Bottomline line: Louie and his supporters are on the wrong side of common sense and decency, and the wrong side of history.

Next year, get out and vote and make this laughable buffoon of an elected official an “ejected” official.

Send Louie home. He’s representing the underbelly of an autocratic movement that is anti-American, and anti-democracy.

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http://iEXPOSED.us

PO Box 721

Scottsville TX 75688

CORONAVIRUS INFO PROVIDED BY DR. JIM HARRIS –10/22/2021

HELLO, I WISH YOU A NICE WEEKEND. 

HOPKINS CITATIONS FOR DELTA PLUS (AY4.2)

UK & “DELTA PLUS Late last week, the UK Health Security Agency released its 25th Technical Briefing on SARS-CoV-2 variants of concern and variants under investigation. Data on a new sublineage of the SARS-CoV-2 Delta variant—newly designated as AY4.2 and sometimes called “Delta Plus”—show incidence has been expanding within the country, accounting for 6% of all samples sequenced. Health officials expect this proportion to increase in the coming weeks, and many in the public health community are watching the sublineage to see how it impacts the COVID-19 epidemiological situation. The UK recently has experienced a drastic increase in new COVID-19 cases, reporting a daily average of 45,461 new cases on October 20, up more than 12,000 cases from 2 weeks ago. Additionally, the number of daily deaths are rising. Reports suggest that an increase in cases among children has been fueling this most recent spike, especially as this age group returned to schools. Notably, vaccine uptake has lagged since early September, although there has been an uptick in average daily vaccinations over the past several days. The UK has a higher vaccination rate than some of its European counterparts, with 79% of the eligible population fully vaccinated.

Public health experts are pleading with the UK government to reinstate COVID-19 restrictions that were rolled back this summer in order to avoid reaching a critical point where the virus becomes much more difficult to contain. The government has pushed back on these calls, saying the UK will not go back to a lockdown scenario and that people should “learn to live with this virus.” In September, Prime Minister Boris Johnson announced a “Plan B” for the country, to be implemented if the National Health Service (NHS) becomes overwhelmed. The plan includes reimplementing some restrictions like mask mandates and vaccine passports but would work to keep major operations running. Others are calling for a “Plan B Plus” that would go a few steps further and include urging people to get vaccinated or get boosters, using the healthcare system wisely, and volunteering to support frontline workers. 

BRAZIL A parliamentary commission of inquiry (CPI) in Brazil is recommending that President Jair Bolsonaro be charged with 9 serious offenses—including charlatanism, incitement to commit crimes, the propagation of pathogenic germs, and crimes against humanity—for allegedly intentionally allowing the COVID-19 pandemic to spread unabated through the country and killing hundreds of thousands of people, according to a 1,180-page final draft of its report. The commission’s senators are scheduled to vote on the final report on October 26, and if approved, the accusation of crimes against humanity will be referred to the International Criminal Court for further investigation. The document also recommends criminal charges for at least 65 other people, including current and former government officials and 3 of President Bolsonaro’s sons. While it is unclear whether the accusations will lead to criminal charges, the report could prove damaging to President Bolsonaro’s reelection campaign. President Bolsonaro, a self-confessed vaccine skeptic, pushed unproven treatments, discouraged mask-wearing and encouraged mass gatherings as COVID-19 incidence increased nationwide. Of the 11-member committee, 7 are members of the opposition, suggesting the report will be approved.

The Pfizer COVID-19 vaccine for kids is coming; here are 6 things to know

(J. Harris: This is a good DMN general article that is readable and informative.)

AND LASTLY:

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CORONAVIRUS INFO PROVIDED BY DR. JIM HARRIS –10/21/2021

CORONAVIRUS INFO PROVIDED BY DR. JIM HARRIS –10/21/2021

Russia orders non-working week after record COVID deaths

(J. Harris: The Covid roller coaster ride continues worldwide. I must conclude that I have overestimated the intelligence of humans. Americans are not the only vaccine-hesitant group; our political division is only one cause of reluctance to trust science, leaders, educators, and local authorities. Many human beings are just not emotionally and intellectually capable of rational behavior and trust. Russia has had an adequate vaccine longer than anyone, and still, the population refuses to trust the science and the leaders. Now, they are again in desperate trouble. It may be that “herd immunity” will never develop against a constantly mutating virus. Constantly upgraded vaccines  will remain  our most viable defense.)

EUROPE SURGE COVID-19 is once again surging in Europe, particularly in the UK and Central and Eastern Europe. The daily incidence at the continent level increased by more than 45% since the most recent low on September 16. Over the past 2 weeks, 16 European countries have reported increases in daily incidence of 25% or greater, including Czechia (+102%), Latvia (+118%), and Poland (+123%) with greater than 100%. Additionally, Ireland and the UK reported increases of 23% and 20% over that period, respectively. Europe is exhibiting similar trends in terms of daily mortality as well, with 9 countries reporting biweekly increases of 50% or more, including Poland (+103%), Romania (+109%), and Luxembourg (+300%) with increases of more than 100%. With the exception of Iceland, Ireland, and the UK, nearly all of these countries are located in the Central and Eastern regions of Europe. As Europe transitions to colder weather and winter holidays, major COVID-19 surges could pose additional risk due to increased social activities and gatherings indoors.

US CDC HOLIDAY GUIDANCE The US CDC on October 15 released new public health guidance for 2021 winter holiday celebrations, with a focus on urging those who are unvaccinated against SARS-CoV-2 to get their shots before traveling or gathering with family and friends. To protect those too young to be eligible for vaccination, the agency recommends all those around them to be vaccinated. According to new data released the same day, the CDC noted that in August, unvaccinated individuals had an 11 times greater risk of dying from COVID-19 than those who were fully vaccinated. Like 2020, the CDC also recommended masking when in crowded indoor settings and trying to be outside as much as possible in group settings. The new guidance was released following some confusion earlier this month, when the CDC mistakenly posted old information to its website. Some public health experts warned that as long as there are gaps in vaccination coverage throughout the country, a winter surge in COVID-19 cases remains a possibility, especially if people do not follow the guidance.

Lastly:

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CORONAVIRUS INFO PROVIDED BY DR. JIM HARRIS –10/20/2021

HELLO,

(J. Harris: Note that East Texas Covid has “burned out” for now.)

*****

(J. Harris: Good HOPKINS summary of recent Covid Vaccine decisions)




 

BOOSTER DOSES The US FDA’s Vaccines and Related Biological Products Advisory Committee during 2 days of meetings last week considered several questions related to booster doses for SARS-CoV-2 vaccines. The panel’s recommendations are not binding, although the FDA generally follows the advice of its committees. ModernaThe vaccine advisory panel on October 14 voted unanimously to endorse a booster dose of Moderna’s SARS-CoV-2 vaccine, administered at least 6 months after the second dose. The vote supports authorizing an additional dose of the vaccine in the same groups authorized for a booster dose of the Pfizer-BioNTech SARS-CoV-2 vaccine, including individuals aged 65 and older, those ages 18 to 64 at a higher risk for severe disease, and people at risk of exposure due to their occupation. The advisory panel also discussed when booster doses should be provided to all adults but concluded it is too soon to make that decision. The Moderna booster under consideration is 50μg, half the dose of the initial 2 shots, while the authorized booster for the Pfizer-BioNTech vaccine is the same formulation as the FDA-approved 2-dose vaccine. Moderna claims a half dose is enough to activate the immune system while still stretching the world’s supply of available vaccines. Data from Moderna show that the booster dose did not produce the 4-fold antibody increase set as a guideline by the FDA for authorizing boosters, but Moderna said it was because of existing high levels of antibodies in study participants. Some panel members expressed concern over some of the data provided by Moderna—including on how best to measure correlates of protection and durability provided by a half dose—but not enough to prevent endorsement of booster doses. Others noted that avoiding public confusion over which vaccines were approved for booster doses and why played a role in their decision. J&J-JanssenDuring a second day of meetings on October 15, the vaccine advisory panel voted unanimously to endorse a second dose of the J&J-Janssen SARS-CoV-2 vaccine for all recipients. This meeting saw more controversy than previous meetings on booster shots for the Pfizer-BioNTech and Moderna SARS-CoV-2 vaccines, with some panelists reportedly unhappy with multiple slides presented by J&J-Janssen that contained data not previously vetted by the FDA. Additionally, the companies presented data on boosters given at 6 months from a study with a sample size of only 17 volunteers. Panelists expressed frustration with and hesitancy to make a decision based on the limited data, but all the panelists agreed that anyone who received the J&J-Janssen vaccine should be eligible for a second dose, with some saying the vaccine should be considered as a 2-dose regimen. The concerns revolved around data showing that a single dose of J&J-Janssen offered lower protection than 2 doses of either the Pfizer-BioNTech or Moderna vaccines.  Mix & MatchFollowing its vote on the J&J-Janssen vaccine, the panel discussed the so-called “mix & match” strategy, which could allow heterologous booster doses for certain populations. Data from an NIH study released last week showed that the antibody levels of those who initially received the J&J-Janssen shot rose 76-fold in 15 days following a booster with Moderna and 35-fold after a booster with Pfizer-BioNTech. By comparison, a second dose of J&J-Janssen only raised antibody levels 4-fold in the same timeframe. It is worth noting that there were concerns because the NIH study results were based on a small number of volunteers and only reported short-term findings. Despite these concerns, some panelists claimed the data are enough to convince them to support a mix & match strategy, something that is fairly common in other countries.  The FDA is expected to authorize boosters for some Moderna and all J&J-Janssen vaccine recipients as early as this week and also could make a decision on the mix & match strategy. The US CDC’s Advisory Committee on Immunization Practices (ACIP) is scheduled to meet this week to make its own recommendations on booster doses, meaning millions more people in the US could be eligible for additional shots by the end of the week.  AND LAST BUT NOT LEASED: 

….

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CORONAVIRUS INFO PROVIDED BY DR. JIM HARRIS –10/19/2021

F.D.A. to Allow ‘Mix and Match’ Approach for Covid Booster Shots

Why Public Health Faces a Crisis Across the U.S.

AY.4 Delta sub-lineage now predominant in UK and Australia, rising in the US

Changes in Cigarette Sales in the United States During the COVID-19 Pandemic

”…The finding shows a surge in cigarette sales during the COVID-19 pandemic. We estimated an increase of about 0.34 pack per month per capita, corresponding to about a 14.1% increase above the expected sales. Excess sales of cigarettes reported in this study align with findings from Nielsen retail tobacco sales data of increases in tobacco sales from April to June 2020 (4). However, this study shows that increases in cigarette sales went beyond the first 3 months of the COVID-19 pandemic and persisted in the 16 months after its onset in March 2020…”

FROM THE WASHINGTON POST 18 OCT:

”…Colin Powell died at 84 of complications from a coronavirus infection. Powell was vaccinated, though he had several factors for a weakened immune response: He was an elderly man and he had been treated in recent years for multiple myeloma, a blood cancer. This event is no reason to avoid vaccination — in fact, as these charts show, as more people are immunized, the risk of death decreases even among the most vulnerable

(J. Harris: Obviously the general was immunocompromised by his Multiple Myeloma and/or Chemo. RIP to a good man.

FROM BECKER:

VACCINE COVERAGE COMPARISONS

FROM HOPKINS:

Safety and Immunogenicity of CpG 1018 and Aluminium Hydroxide-adjuvanted SARS-CoV-2 S-2P Protein Vaccine MVC-COV1901: Interim Results of a Large-scale, Double-blind, Randomised, Placebo-controlled Phase 2 Trial in Taiwan (Lancet Respiratory Medicine) MVC-COV1901, a recombinant protein vaccine containing pre-fusion-stabilised spike protein S-2P adjuvanted with CpG 1018 and aluminium hydroxide, has been shown to be well tolerated with a good safety profile in healthy adults aged 20–49 years in a phase 1 trial, and provided a good cellular and humoral immune responses. We present the interim safety, tolerability, and immunogenicity results of a phase 2 clinical trial of the MVC-COV1901 vaccine in Taiwan.

FROM ETBU WHERE COVID IS RARE:

AND LAST BUT NOT LEASED: 

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Equal parts of stupid and evil

 Opinion: What do you get when you mix equal parts of stupid and evil?

By George Smith  — October 18, 2021

You may consider it a rhetorical question because there are as many potential answers as there are people.

But several answers quickly  pop to my mind: 1. Marjorie Taylor Green 2. Josh Hawley 3. Lauren Boebert.

These three have no redeeming social value, and, along with a choir of messengers singing the praises of and clamoring for the blessing of their cult leader Donald Trump, readily stir up a cauldron of lies, intellectual fraud, divisiveness and lack of the human emotion of empathy.

In a phrase, they are fallen angels preaching that chaos is better than peace, purveyors of wrong-headed thinking, trumpeteers of the dismantling of democracy.

They, along with the likes of Chip Roy, Louie Gohmert and Joni Ernst, are the congressional apostles to Trump’s Mephistopheles; all have attained a certain degree of notoriety due to their ability to open their mouths and insert BOTH feet simultaneously.

A couple of these have obtained cult status by performing their feet-in-mouth trick while having their heads inserted in Trump’s posterior.

Other so-called Republicans, like Stephen Miller, Ted Cruz and Mario Rubio, are evil, but cannot be called  stupid by any measurement. That, honestly, is doubly sad in that they willingly help set the destructive agenda of the party’s evil path m, one paved with lies, lies and more lies. It is their choice to put the desire for personal power over the betterment of all people.

But their intelligence has been wasted by their devotion to a cult leader rather than bow to those in the bipartisan choir working to encourage them to leave the COT (Cult of Trump).

They, like Leader Trump, are fallen angels, torn between satanic pride, dark despair and controlling the actions of those who have never met a conspiracy theory they didn’t like.

This round of political shenanigans was predicted long ago in a book chic

 of history, cool stories, miracles and prophecies, a book many conservatives praise but do not embrace — the Bible.

“And the great dragon was thrown down, the serpent of old who is called the devil and Satan, who deceives the whole world; he was thrown down to the earth, and his angels were thrown down with him.”

                             — Revelations 12:9

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PO Box 721

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CORONAVIRUS INFO PROVIDED BY DR. JIM HARRIS –10/18/2021

READABLE VACCINE INFORMATION

Why many Black Americans changed their minds

Association between digital smart device use and myopia: a systematic review and meta-analysis

(J. Harris: Impt. article about near sighted vision. Not related to Covid. )

HISTORICAL MEDICAL QUARANTINE ARTICLE

(J. Harris: Readable and interesting. Sent to me by a Houston area internist.)

LONG COVID GENERAL ARTICLE RE TREATMENT

LASTLY:

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