1. US has a new dominant COVID-19 strain


1. Your Lingering Covid Questions, Answered

(J. Harris: Good general reference to keep for Covid. Readable.Keep.)

2. Some universities and schools in the U.S. are reimposing indoor mask mandates.

”…Another Omicron subvariant, known as BA.2.12.1, which spreads more rapidly than previous versions, has become the dominant form of the virus among new U.S. cases, according to federal estimates. For the first time since February, the country is now averaging more than 100,000 new confirmed cases a day, according to a New York Times database, and the widening use of at-home testing means the true number of infections is probably higher…”

3. The White House pushes to get Paxlovid pills into more Covid patients’ hands.

”…Significant obstacles persist in getting Paxlovid to everyone who could benefit from it; more than a million courses of Paxlovid purchased by the government are still available, according to data collected by the Department of Health and Human Services. Because of vague eligibility guidelines that are open to broad interpretation — the medication is authorized for people 12 and older with “mild-to-moderate” Covid-19 who are at risk of severe illness — some doctors are hesitant to prescribe the pill, or require extensive consultation…”


1. MONKEYPOX OUTBREAKS UPDATE Read our latest update from May 23 on the monkeypox outbreaks. A new fact sheet also is available. We will continue to analyze the situation and provide updates, as needed. If you would like to receive these updates, please sign up here.


Canada’s Quebec confirms 15 cases of monkeypox

The Canadian province of Quebec has confirmed 15 cases of monkeypox as of Monday, the provincial health department said on Tuesday.


1. Cardiac Complications More Common After COVID-19 Than Vaccination

2. Transmission and Infectious SARS-CoV-2 Shedding Kinetics in Vaccinated and Unvaccinated Individuals

”…Fully vaccinated individuals had a shorter duration of viable viral shedding and a lower rate of secondary transmission than partially vaccinated or unvaccinated individuals.”

3. Viral Antigen and Inflammatory Biomarkers in Cerebrospinal Fluid in Patients With COVID-19 Infection and Neurologic Symptoms Compared With Control Participants Without Infection or Neurologic Symptoms

” These results suggest that viral components may contribute to central nervous system immune responses without direct viral invasion and highlight the clinical importance of neurologic symptoms.”

4. Association Between the COVID-19 Pandemic and Disparities in Access to Major Surgery in the US

”These findings suggest that the early response to the pandemic did not increase disparities in access to surgical care.”


COVID-19 Rebound After Paxlovid Treatment

”…A brief return of symptoms may be part of the natural history of SARS-CoV-2 (the virus that causes COVID-19) infection in some persons, independent of treatment with Paxlovid and regardless of vaccination status…”


What COVID Hospitalization Numbers Are Missing, By Ed Yong

”…Even when missing people can be replaced, missing knowledge cannot. The pandemic pushed many veteran health-care workers into early retirement, lowering the average experience level in American hospitals. “I don’t think the public really understands how great the loss of this generational knowledge is,” Cabrera told me. In her current job, she had just four days of orientation, which she describes as “shockingly short,” from some people who had been in the ER for less than a year. When inexperienced recruits are trained by inexperienced staff, the knowledge deficit deepens, and not just in terms of medical procedures. The system has also lost indispensable social savvy—how to question an inappropriate decision, or recognize when you’re out of your depth—that acts as a safeguard against medical mistakes. And with established teams now ruptured by resignations, many health-care workers no longer know—or trust—the people at their side….Absurdly, it’s often hard to get people out of the hospital, Sara Wolfson, a geriatrician at Nebraska Medicine, told me. Many elderly patients still need care after they’ve stabilized, but it’s hard to discharge them, because long-term care facilities and home-health agencies are also incredibly short-staffed and unable to accommodate new patients….”



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