NYT NOT OUT YET FOR SUNDAY NUMBERS:
1. Health Impacts Of The Russian Invasion In Ukraine: Need For Global Health Action (Lancet) More than 1 month since Russia began its illegal invasion of Ukraine the tragic human suffering and loss of life are clear. Each day brings more death, injuries, and stories of people fighting for their lives. The implications of the war extend beyond the military and civilian casualties. There are geopolitical, financial, infrastructural, and health impacts. And the effects of this war, particularly on health and health care within and outside Ukraine, will continue long after violent conflict ends.
2. COVID Antibody Drugs Work Best When Given As Early As Possible (Nature)
A first-of-its-kind analysis has a clear message about when to give the COVID-19 therapies called monoclonal antibodies: the earlier people get this type of treatment, the better they fare1. The study, based on dozens of clinical trials, also suggests that many antibody therapies might work at doses much lower than those usually administered. This finding could have far-reaching implications given monoclonal antibodies’ extraordinarily high cost and their ability to keep people with COVID-19 out of hospital. The study was posted on the medRxiv preprint server on 22 March and has not yet been peer reviewed. “We’ve been giving huge doses of antibodies,” says Miles Davenport, an immunologist at the University of New South Wales in Sydney, Australia, who co-led the study. “You could get away with using much, much lower doses.”
3. Narrowing The Vaccine Gap As Boosters Begin For People Over 50 (STAT News) The Food and Drug Administration this week authorized a second booster for individuals 50 and older. Although some people over the age of 50 are mulling whether and how soon to get their fourth jab, a significant vaccine gap exists within this group which needs to be addressed. There are 118.5 million Americans over the age of 50; 18.4 million (15%) of these individuals are not fully vaccinated and 59 million (50%) have not received their first booster.
1. Deliberate infection trial finds COVID symptoms don’t indicate viral shedding
”…The results suggest that vaccines are effective in protecting against symptomatic and severe disease, but that, with high vaccination rates, standard surveillance metrics may not accurately estimate the spread of SARS-CoV-2. Thus, wastewater surveillance may be important as an early warning of virus circulation. These results strengthen the scientific basis of the recommendations from the Centers for Disease Control and Prevention National Wastewater Surveillance System and European Commission to establish systematic SARS-CoV-2 wastewater surveillance networks…”
Catastrophic Health Consequences of the War in Ukraine
”…attacks on health care facilities, personnel, and patients and other civilians represent violations of international health law and are considered war crimes. They also review issues related to accountability for perpetrators of these attacks and emphasize the pressing need to provide international humanitarian health aid to Ukraine and to assist refugees who have fled the country as well as those who have been internally displaced.attacks on health care facilities, personnel, and patients and other civilians represent violations of international health law and are considered war crimes. They also review issues related to accountability for perpetrators of these attacks and emphasize the pressing need to provide international humanitarian health aid to Ukraine and to assist refugees who have fled the country as well as those who have been internally displaced…”
Rudeness is on the rise — why?
”…The Atlantic’s Olga Khazan spoke with more than a dozen experts on crime, psychology and social norms to suss out contributing factors to the spike in poor behavior, which she details in her piece, “Why People Are Acting So Weird,” published March 30. …”We’re more likely to break rules when our bonds to society are weakened,” Robert Sampson, PhD, a Harvard sociologist, told Ms. Khazan. “When we become untethered, we tend to prioritize our own private interests over those of others or the public….”
(J. Harris: Good summary article and a quick read.)
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