Israeli experts recommend offering a fourth vaccine dose to people age 18 and over.

”…JERUSALEM — A medical panel advising the Israeli government has recommended making fourth coronavirus vaccine doses available to people age 18 and over, the Health Ministry said on Tuesday, citing what it suggested were some early signs of the effectiveness of an additional shot in helping prevent serious illness…The recommendation, which the ministry has yet to approve, comes weeks after Israel began offering fourth doses to people age 60 and over, as well as to medical workers and people with weakened immune systems, as it braced for a surge of infections from the highly contagious Omicron variant. It was the first country to offer such additional shots so broadly…The panel recommended offering a fourth shot to people age 18 and above at least five months after they recover from Covid-19 or receive a third vaccine shot. About 600,000 Israelis have already received a fourth dose.


1 Rich Countries’ Access to Foreign Nurses During Omicron Raises Ethical Concerns, Group Says (Reuters) The Omicron-fuelled wave of COVID-19 infections has led wealthy countries to intensify their recruitment of nurses from poorer parts of the world, worsening dire staffing shortages in overstretched workforces there, the International Council of Nurses said. Sickness, burnout and staff departures amid surging Omicron cases have driven absentee rates to levels not yet seen during the two-year pandemic, said Howard Catton, CEO of the Geneva-based group that represents 27 million nurses and 130 national organizations. To plug the gap, Western countries have responded by hiring army personnel as well as volunteers and retirees but many have also stepped up international recruitment as part of a trend that is worsening health inequity,

2. Association Between 3 Doses of mRNA COVID-19 Vaccine and Symptomatic Infection Caused by the SARS-CoV-2 Omicron and Delta Variants (JAMA) Among individuals seeking testing for COVID-like illness in the US in December 2021, receipt of 3 doses of mRNA COVID-19 vaccine (compared with unvaccinated and with receipt of 2 doses) was less likely among cases with symptomatic SARS-CoV-2 infection compared with test-negative controls. These findings suggest that receipt of 3 doses of mRNA vaccine, relative to being unvaccinated and to receipt of 2 doses, was associated with protection against both the Omicron and Delta variants, although the higher odds ratios for Omicron suggest less protection for Omicron than for Delta.

Effect of Noninvasive Respiratory Strategies on Intubation or Mortality Among Patients With Acute Hypoxemic Respiratory Failure and COVID-19

Question  What is the effect of initial noninvasive respiratory strategies using continuous positive airway pressure (CPAP) or high-flow nasal oxygen (HFNO), compared with an initial strategy of conventional oxygen therapy, on the risk of tracheal intubation or mortality among hospitalized adults with acute hypoxemic respiratory failure due to COVID-19?

Findings  In this randomized clinical trial of 1273 patients, the composite primary outcome of tracheal intubation or mortality within 30 days occurred in 36% of the patients in the CPAP group compared with 44% in the conventional oxygen therapy group, a difference that was statistically significant, and occurred in 44% in the HFNO group compared with 45% in the conventional oxygen therapy group, a difference that was not significantly different.

Meaning  Among patients with acute hypoxemic respiratory failure and COVID-19, an initial strategy of CPAP significantly reduced the risk of tracheal intubation or mortality compared with conventional oxygen therapy, but there was no significant difference between an initial strategy of HFNO compared with conventional oxygen therapy.

(J. Harris: CPAP, similar to those devices that some folks use for Sleep Apnea was sometimes helpful in treating Covid respiratory problems. A complex editorial following the article discusses the issues remaining with Covid induced respiratory failure.)

From the MNM Today:

2021 report: Northeast Texas home to higher mortality rates compared to the state, country

2021 report: Northeast Texas home to higher mortality rates compared to the state, country

J. Harris: Frightening.  



2. The CDC defines immunocompromised at the following links:

3. If you are looking for a specific brand you can go to enter your zip code and find a vaccine provider.



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