”…In summary, COVID-19-related deaths were extremely uncommon in those fully vaccinated with either BNT162b2 or ChAdOx1 nCoV-19. Most individuals who died after two doses of COVID-19 vaccine were older than 75 years and had multiple comorbidities. These results are similar to the risk profile for mortality in unvaccinated individuals with COVID-19 infection,… and in vaccinated individuals who have received one dose of vaccine.5 Risk of COVID-19-related death is therefore not completely eliminated when fully vaccinated; the results of this study suggest the importance of continued caution and non-pharmaceutical interventions, in particular for older adults with multiple comorbidities.
(J. Harris: A newer vaccine currently used in India as well. See ”3”below.
1. New From the HOPKINS Center Together with our partner The Council on Foreign Relations, we released a new report urging governments, multilateral and international institutions, and private actors to act immediately to strengthen planning for future pandemic vaccines by incorporating lessons learned from successes and failures of the current global rollout of COVID-19 vaccines. The new report, Navigating the World that COVID-19 Made: A Strategy for Revamping the Pandemic Research and Development Preparedness and Response Ecosystem, identifies how the COVID-19 pandemic has exposed and redefined the realities of the global vaccine research, development, production and delivery ecosystem, one which has so far failed in rapid, equitable allocation and distribution of vaccines globally.Read the Report 2. The search for people who never get COVID As described in a paper in Nature Immunology1 this month, an international team of scientists has launched a global hunt for people who are genetically resistant to infection with the pandemic virus. The team hopes that identifying the genes protecting these individuals could lead to the development of virus-blocking drugs that not only protect people from COVID-19, but also prevent them from passing on the infection…The first step is to narrow the search to people who have been exposed, without protection, to a sick person over an extended period, and have not tested positive or mounted an immune response against the virus. Of particular interest are people who shared a home and bed with an infected partner — pairs known as discordant couples. 3. Novavax COVID-19 Vaccine Receives First Emergency Use Authorization (Reuters) Novavax Inc (NVAX.O) and partner Serum Institute of India said on Monday they received emergency use authorization for their COVID-19 vaccine in Indonesia, making it the first approval anywhere in the world for Novavax. Shares of Novavax rose about 11% before the opening bell after the company also said it had filed an application for emergency use for the vaccine to Canada and the European Medicines Agency. 4. Community Transmission and Viral Load Kinetics of the SARS-CoV-2 Delta (B.1.617.2) Variant in Vaccinated and Unvaccinated Individuals in the UK: a Prospective, Longitudinal, Cohort Study (Lancet Infectious Diseases) We aimed to investigate transmission and viral load kinetics in vaccinated and unvaccinated individuals with mild delta variant infection in the community. The SAR (secondary attack rate) in household contacts exposed to the delta variant was 25% (95% CI 18–33) for fully vaccinated individuals compared with 38% (24–53) in unvaccinated individuals. Vaccination reduces the risk of delta variant infection and accelerates viral clearance. Nonetheless, fully vaccinated individuals with breakthrough infections have peak viral load similar to unvaccinated cases and can efficiently transmit infection in household settings, including to fully vaccinated contacts. Host–virus interactions early in infection may shape the entire viral trajectory. NEW COVID CASES IN HARRISON COUNTY: Update on and Future Directions for Use of Anti–SARS-CoV-2 Antibodies: National Institutes of Health Summit on Treatment and Prevention of COVID-19 (J. Harris: I did not read.) LAST BUT NOT LEASED: MORE MAN V WOMAN “TRUISMS”MONEY A man will pay $2 for a $1 item he needs A woman will pay $1 for a $2 item that she doesn’t need but it’s on sale. BATHROOMS A man has six items in his bathroom: toothbrush and toothpaste, shaving cream, razor, a bar of soap, and a towel. The average number of items in the typical woman’s bathroom is 337. A man would not be able to identify more than 20 of these items.
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