CORONAVIRUS INFO PROVIDED BY DR. JIM HARRIS – 03/02/2021

FIRST VACCINE SHOTS ARE AVAILABLE AT CIVIC CENTER TOMORROW. MANY APPOINTMENTS AVAILABLE FOR THE 1A AND 1B FOLKS.

“The Marshall Harrison County Health District has been notified of an allocation of 400 doses of the Moderna COVID-19 vaccine for this week from the Texas Department of State Health Services (DSHS). A community COVID-19 vaccination clinic will be held on Wednesday, March 3, 2021, BY APPOINTMENT ONLY.

HOW TO REGISTER: Pre-registration is REQUIRED online at https://www.signupgenius.com/go/70A0B4AAFA622A2FB6-harrison4 to secure a vaccination appointment. ⁠You can also go https://mhchd.org/ and click on the Sign Up button.

(J. Harris: Apparently the 2nd Shot Moderna Clinic will coincide with this new event as already scheduled)

HOPKINS CITED:

1. Johnson & Johnson Has Planned Trials of Its Vaccine That Will Include Infants (New York Times) Johnson & Johnson plans to test its coronavirus vaccine in infants and even in newborns, as well as in pregnant women and in people who have compromised immune systems. The bold plan for expanded clinical trials met with the approval of Dr. Ofer Levy, director of the Precision Vaccines Program at Harvard’s Boston Children’s Hospital and a member of the Food and Drug Administration advisory committee that reviewed the company’s vaccine data.

2. Estimating Risk of Mechanical Ventilation and In-hospital Mortality Among Adult COVID-19 Patients Admitted to Mass General Brigham: The VICE and DICE Scores (EClinical Medicine) We found four factors to be independently predictive for mechanical ventilation requirement (diabetes mellitus, SpO2:FiO2 ratio, C-reactive protein, and lactate dehydrogenase), and 10 factors to be predictors of in-hospital mortality (age, male sex, coronary artery disease, diabetes mellitus, chronic statin use, SpO2:FiO2 ratio, body mass index, neutrophil to lymphocyte ratio, platelet count, and procalcitonin). Using these factors, we constructed the VICE and DICE risk scores, which performed with C-statistics of 0.84 and 0.91, respectively.

Could our immune system be why COVID-19 is so deadly?

“…Cytokine storms are not unique to SARS-CoV-2 infection; they can be found in most of the critical human coronaviruses and influenza. A subtype outbreaks of the past two decades.

“Cytokines are small proteins that tightly regulate our immune system and how our body reacts to internal or external stress, such as cancer, inflammation, or infection. Cytokines act as conductors, orchestrating our immune response when infected with viruses. One of their roles is to cause inflammation, which is part of the healing process of many infections and injuries

“…Respiratory viruses all activate antiviral responses in the body but there are differences in how each virus attempts to evade the attention of the immune system. The most common strategy is to confuse, or specifically attack, crucial immune response mechanisms—such as the release of cytokines….the researchers’ analysis found specific immune mechanisms that make SARS-CoV-2 uniquely dangerous….”

(J.Harris: These folks are evaluating the various types of “Storm” and developing a data bank or Map to enhance future studies and classifications. I include this material since it presents a good explanation of Cytokinetics.)

Late info:  

There are a lot of openings for tomorrow!

The Marshall Harrison County Health District has been notified of an allocation of 400 doses of the Moderna COVID-19 vaccine for this week from the Texas Department of State Health Services (DSHS). A community COVID-19 vaccination clinic will be held on Wednesday, March 3, 2021, BY APPOINTMENT ONLY.

HOW TO REGISTER: Pre-registration is REQUIRED online at https://www.signupgenius.com/go/70A0B4AAFA622A2FB6-harrison4 to secure a vaccination appointment. ⁠You can also go https://mhchd.org/ and click on the Sign Up button.

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