Male Sex Identified by Global COVID-19 Meta-analysis As a Risk Factor for Death and ITU Admission (Nature Communications) Here, we present a meta-analysis of 3,111,714 reported global cases to demonstrate that, whilst there is no difference in the proportion of males and females with confirmed COVID-19, male patients have almost three times the odds of requiring intensive treatment unit (ITU) admission (OR = 2.84; 95% CI = 2.06, 3.92) and higher odds of death (OR = 1.39; 95% CI = 1.31, 1.47) compared to females. With few exceptions, the sex bias observed in COVID-19 is a worldwide phenomenon. An appreciation of how sex is influencing COVID-19 outcomes will have important implications for clinical management and mitigation strategies for this disease.
South Korea Scrambles to Build Container Hospital Beds to Combat Third COVID-19 Wave (Reuters) South Korea authorities scrambled on Thursday to build hospital beds in shipping containers to ease strains on medical facilities stretched by the latest coronavirus wave, which shows little sign of abating with 682 new cases. The resurgence of infections has rekindled concerns about an acute shortage of hospital beds, prompting Seoul city to begin installing container beds for the first time since the start of the pandemic.
While coronavirus disease 2019 (COVID-19) is predominantly self-limited, up to 20% of symptomatic individuals will progress to severe or critical disease with clinical manifestations including pneumonia, acute respiratory distress syndrome, multiorgan system dysfunction, hypercoagulation, and hyperinflammatory manifestations. ..Recent attention has been focused on the potential of early treatment …Remdesivir requires daily infusions for up to 10 days4 and is not suitable for an ambulatory setting. Dexamethasone has not been tested in early, mild disease, but its immune-suppressive effects could potentially worsen clinical outcomes in this setting…. (need to )develop new drugs that can be dosed without requiring intravenous infusions or other complex maneuvers. Effective treatments that require infusion may be the first approved for clinical use and will have a significant public health impact. However, for the greatest benefit, treatments will need to be administered easily and made available widely at low cost—(J. Harris: Multiple trials of various modalities of acute treatment are being performed all over the world. I expect success. )
The former new York mayor said he received remdesivir, dexamethasone and “exactly the same” treatment that Trump got in October when he was hospitalized, which the resident has often credited for his speedy recovery.
“The minute I took the cocktail yesterday, I felt 100 percent better,” Giuliani said in a Tuesday afternoon interview with WABC, a New York talk radio station. “It works very quickly. Wow! … By the next morning, I felt like I was 10 years younger.”
(J. Harris: It must have been a Manhattan Cocktail?)
IMPOSSIBILITIES IN THE WORLD
1) You can’t count your hair.
2) You can’t wash your eyes with soap.
3) You can’t breathe through your nose when your tongue is out.
(Put your tongue back in your mouth, you silly person.)
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