July 14, 2020



Monday Marshall had 4 new cases and 2 deaths. Longview was about the same. Smith County had 142 new cases!

HOPKINS:1. SARS-CoV-2 Seroprevalence Rates of Children in Louisiana During the State Stay at Home Order.(MedRxiv) In a large retrospective study, the seropositivity prevalence for SARS-CoV-2 in children in Louisiana during the mandated Stay At Home Order was 7.6%. Residence location, race, and lower socioeconomic factors were linked to more frequent seropositivity in children and correlated to regional COVID-19 case rates. Thus, a significant number of children in Louisiana had SARS-CoV-2 infections that went undetected and unreported and may have contributed to virus transmission.

2. Reopened Schools in Europe and Asia Have Largely Avoided Coronavirus Outbreaks. They Have Lessons for the U.S.(Washington Post) Many countries around the world are pushing ahead with plans for full-time, full-capacity, in-person classes, after having largely avoided coronavirus outbreaks linked to schools during more tentative reopenings in the spring. From Belgium to Japan, schools are abandoning certain social distancing measures, such as alternate-day schedules or extra space between desks.

3…. nine centers offering free, rapid COVID-19 tests in low-income neighborhoods with high proportions of racial and ethnic minorities. Roughly 35% of tests performed at a center in Phoenix and 30% in Atlanta had come back positive as of 23 June, he said. Nationwide, only 8.8% of tests were positive last week, according to the U.S. Centers for Disease Control and Prevention (CDC), although last week Arizona reported a 21% positive rate.

4. NIAID Merges Four Clinical Trials Networks into COVPN, Focusing on COVID-19 Vaccine and Antibody Testing (Homeland Preparedness News) Streamlining processes this week, the National Institute of Allergy and Infectious Diseases (NIAID) created a new clinical trials network to gather thousands of volunteers together for testing of various investigational vaccines and monoclonal antibodies for use against COVID-19. NIAID developed the COVID-19 Prevention Trials Network (COVPN) from four existing clinical trials networks: the HIV Vaccine Trials Network, the HIV Prevention Trials Network, the Infectious Diseases Clinical Research Consortium and the AIDS Clinical Trials Group. 

5. Immunity to COVID-19 Could Disappear in Months, a New Study Suggests (MIT Technology Review) Immunity to covid-19 may be short-lived, according to a new longitudinal study of people who have caught the disease and recovered.

6.Immunity to covid-19 could disappear in months, a new study suggestsThe study: Researchers at King’s College London repeatedly tested 96 patients and health-care workers at Guy’s and St Thomas’ NHS Foundation Trust for antibodies between March and June. All the participants were confirmed to have had covid-19, either via a PCR test or a positive antibody test. The researchers found that levels of virus-fighting antibodies peaked about three weeks after symptoms started and then rapidly fell away. Although 60% of participants produced a “potent” antibody response while they had covid-19, only 17% had the same level of potency at the end of the three-month testing period. Antibody levels were higher and longer-lasting in people who had had more severe cases of covid-19. For some milder cases, it was impossible to detect any antibodies at all at the end of the three months. The research is published in a preprint paper in medRxiv, which means the findings have yet to be subjected to peer review.

What it means: The study raises the prospect that, like other coronaviruses, covid-19 could reinfect people repeatedly. If that’s the case, “herd immunity” may never arrive, either through a one-shot vaccine or through community spread of the virus, as any protective antibodies would wane with time. However, antibodies are not the only way people can fight off covid-19. T cells, which seek and destroy cells infected with SARS-CoV-2, could also provide some protection. In short, we have not yet generated enough data from patients to be able to draw conclusions on immunity with a high degree of certainty. There have been anecdotal reports of people catching covid-19 for a second time, but none have been confirmed.

At least 132,000 people have died from coronavirus in the U.S.
Good interactive chart whereby you can look up any state in a quick and simple manner and follow what’s happening. In the US,  Texas is second only to Arizona (and perhaps Hell) in disease and death at the present time. Florida is coming on. 

The guy who invented the door knocker got a no-bell prize.

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